Our Leadership Team

Healthcare executive who founded and sold three companies worth over $220 million. Sal J. Rafanelli, RPh, is a seasoned healthcare executive, pharmacist, and serial entrepreneur with a proven track record of driving innovation in the pharmaceutical and medical device sectors. As President & CEO, Sal has founded and led three successful companies in the infusion and specialty pharmacy space, focusing on drug delivery, clinical care, and patient outcomes. His ventures have consistently addressed critical industry challenges by developing solutions that enhance the patient experience while improving cost-efficiency. Sal’s leadership has led to the strategic sale of all three companies to public corporations or private equity firms, with a combined valuation of over $220 million.

Accomplished Executive Leader with 25+ Years in Pharmaceuticals. Seasoned executive with over 25 years of experience in both branded and generic pharmaceuticals, demonstrating a proven track record of driving success. Expert in managing $300+ million P&L and leading sales and marketing teams to accelerate the adoption of over 30 products in key therapeutic areas including rare diseases, oncology, complex injectables, and oral solids. Leslie oversaw pricing and contracting strategies across 80+ accounts, including top Retail, Oncology, Wholesale, Long-Term Care, and Hospital GPOs. Leslie was also instrumental in advancing both Winthrop and Greenstone llc position as a top generic player. Leslie brings his tremendous talent to Lotus Therapeutics serving as Chief Growth Officer.

A seasoned financial expert with 42 years of experience in accounting, tax, and business consulting. Joe Bissonnette, CPA, brings 42 years of expertise in accounting, tax, and business consulting to his role as Chief Financial Officer. After spending the first 15 years of his career in audit, controllership, and financial management across various industries, he founded his own firm, Joseph C. Bissonnette & Co. CPAs, and became a partner at Audibert, Bissonnette & Co. CPAs. His expertise includes financial analysis, business planning, tax, and management consulting. A graduate of the University of Connecticut School of Business, Joe has been instrumental in establishing the accounting, tax, and management systems at Speranza Therapeutics, where he oversees all financial planning and tax operations.

Hiring in Progress

Highly skilled IT Executive with 25+ years’ experience in the healthcare and pharmacy industries. Scott Kalcic has more than 25 years of information technology management and consulting experience with extensive knowledge in IT systems design and implementation, organizational and operational management, security, and regulatory compliance. Scott began his career in public accounting where he quickly rose to the rank of executive prior to opening a successful IT consulting practice.  He has extensive experience in the implementation of cutting-edge technologies, IT organizations and operations at the enterprise level.