Our Leadership Team

Healthcare executive who founded and sold three companies worth over $220 million. Sal J. Rafanelli, RPh, is a seasoned healthcare executive, pharmacist, and serial entrepreneur with a proven track record of driving innovation in the pharmaceutical and medical device sectors. As President & CEO, Sal has founded and led three successful companies in the infusion and specialty pharmacy space, focusing on drug delivery, clinical care, and patient outcomes. His ventures have consistently addressed critical industry challenges by developing solutions that enhance the patient experience while improving cost-efficiency. Sal’s leadership has led to the strategic sale of all three companies to public corporations or private equity firms, with a combined valuation of over $220 million.

Accomplished Executive Leader with 25+ Years in Pharmaceuticals. Seasoned executive with over 25 years of experience in both branded and generic pharmaceuticals, demonstrating a proven track record of driving success. Expert in managing $300+ million P&L and leading sales and marketing teams to accelerate the adoption of over 30 products in key therapeutic areas including rare diseases, oncology, complex injectables, and oral solids. Leslie oversaw pricing and contracting strategies across 80+ accounts, including top Retail, Oncology, Wholesale, Long-Term Care, and Hospital GPOs. Leslie was also instrumental in advancing both Winthrop and Greenstone llc position as a top generic player. Leslie brings his tremendous talent to Lotus Therapeutics serving as Chief Growth Officer.

Joseph C. Bissonnette is a seasoned Accounting, Finance, Management, and Tax Executive with over 40 years of diverse experience. Specializing in accounting systems, GAAP compliance, financial reporting, cost analysis, budgeting, strategic planning, M&A, tax preparation, and contract negotiations, he excels at coordinating financial systems and collaborating with legal and financial professionals. Currently, Joseph serves as CFO of Speranza Therapeutics Inc., overseeing finance, accounting, and tax operations while driving growth and investor relations. Previously, he founded and led Joseph C. Bissonnette & Co CPA’s LLC for 30 years, providing tailored accounting and tax services, and later transitioned clients after its sale in 2020. His early career included controller and audit roles, where he developed financial systems and fraud detection expertise.

Joseph holds a Bachelor’s in Accounting and Finance from the University of Connecticut and is a CPA since 1995. He is an active member of the AICPA, CTCPA, and NATP. Known for his strategic financial leadership, Joseph’s ability to deliver precise reporting, foster profitability, and drive organizational success makes him a trusted advisor and asset in his field. His dedication to excellence and collaborative approach underscores his reputation as a distinguished financial executive.

Hiring in Progress

Highly skilled IT Executive with 25+ years’ experience in the healthcare and pharmacy industries. Scott Kalcic has more than 25 years of information technology management and consulting experience with extensive knowledge in IT systems design and implementation, organizational and operational management, security, and regulatory compliance. Scott began his career in public accounting where he quickly rose to the rank of executive prior to opening a successful IT consulting practice.  He has extensive experience in the implementation of cutting-edge technologies, IT organizations and operations at the enterprise level.